Title

The Potential for Inteins as Antimicrobial Targets

Presenter Information

Maddie BlanfordFollow

Academic Level at Time of Presentation

Senior

Major

Biology

Minor

Chemistry

List all Project Mentors & Advisor(s)

Christopher Lennon

Presentation Format

Oral Presentation

Abstract/Description

Intervening polypeptides, also known as inteins, are a genetic component in proteins essential for survival in many bacteria, viruses, archaea, and single-celled eukaryotes. Inteins catalyze their own removal from the polypeptide chain which then allows for proper functioning of the protein. By inhibiting this removal we can disrupt function in the protein, thereby disrupting function of the host organism.

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The Potential for Inteins as Antimicrobial Targets

Intervening polypeptides, also known as inteins, are a genetic component in proteins essential for survival in many bacteria, viruses, archaea, and single-celled eukaryotes. Inteins catalyze their own removal from the polypeptide chain which then allows for proper functioning of the protein. By inhibiting this removal we can disrupt function in the protein, thereby disrupting function of the host organism.