JCSET | Projects in Biomathematics

Title

Viewing Action Potentials Through the Hodgkin-Huxley Model of Excitability

Presenter Information

Morgan MarsFollow

Academic Level at Time of Presentation

Senior

Major

Chemistry/Biochemistry

Minor

Cellular Biology

List all Project Mentors & Advisor(s)

Dr. Mccarthy

Presentation Format

Event

Abstract/Description

The Hodgkin-Huxley Model of Excitability is a quantitative description of electrical excitability in nerve cells which incorporates visuals to predict results regarding voltage-gated structures of ion channels . Combining phenomenological description and mathematical modeling yields the diversity and distribution of voltage gated ion channels in muscle and nerve cells. While action potential follows an all-or-none mechanism, stimuli can vary the action potential. This model is essential for understanding the mechanisms these channels use when initiating action potentials. Through observation of the voltage-gated ion channels and utilization of this model, proper research can be done to alleviate degenerative diseases in the brain.

Spring Scholars Week 2022 Event

Principles of Biomathematics

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Viewing Action Potentials Through the Hodgkin-Huxley Model of Excitability

The Hodgkin-Huxley Model of Excitability is a quantitative description of electrical excitability in nerve cells which incorporates visuals to predict results regarding voltage-gated structures of ion channels . Combining phenomenological description and mathematical modeling yields the diversity and distribution of voltage gated ion channels in muscle and nerve cells. While action potential follows an all-or-none mechanism, stimuli can vary the action potential. This model is essential for understanding the mechanisms these channels use when initiating action potentials. Through observation of the voltage-gated ion channels and utilization of this model, proper research can be done to alleviate degenerative diseases in the brain.