JCSET | Sigma Xi Poster Competition

Title

Reactive Chlorine Species Reversibly Inhibit DnaB Protein Splicing in Mycobacteria

Presenter Information

james goetzFollow

Academic Level at Time of Presentation

Senior

Major

Pre-med/Biology

Minor

Chemistry

List all Project Mentors & Advisor(s)

Dr. Christopher Lennon

Presentation Format

Poster Presentation

Abstract/Description

Inteins, also known as intervening proteins, are genomic protein elements with self-catalytic activity within all three domains of life. Inteins act as environmental control switches where the splicing of the intein, under favorable conditions, allows for the host protein to function properly. This study examined the DnaB intein of M. smegmatis and how its splicing is affected by reactive chlorine species.

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Sigma Xi Poster Competition

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Reactive Chlorine Species Reversibly Inhibit DnaB Protein Splicing in Mycobacteria

Inteins, also known as intervening proteins, are genomic protein elements with self-catalytic activity within all three domains of life. Inteins act as environmental control switches where the splicing of the intein, under favorable conditions, allows for the host protein to function properly. This study examined the DnaB intein of M. smegmatis and how its splicing is affected by reactive chlorine species.