Date on Honors Thesis

Spring 5-2024

Major

Pre-Veterinary Medicine

Minor

Chemistry

Examining Committee Member

Dr. Laura Hoffman, Advisor

Examining Committee Member

Dr. Johanna Choate, Committee Member

Examining Committee Member

Mrs.Tara Joiner, Committee Member

Abstract/Description

This research aimed to statistically analyze the relationship between stem cell therapy and chronic renal failure in a sample of canine and feline patients. Stem cell therapy is a burgeoning field in both human and veterinary medicine, seeking mainly to better understand disease incidence and repair damaged tissues, such as those involved in spinal cord injuries and Alzheimer’s disease. In relation to veterinary medicine, prior research suggests that stem cell therapy has potential to be an effective tool against diseases such as acute kidney injury and chronic kidney disease. This project examined how autologous adipose-derived mesenchymal stem cells affected the rehabilitation of the patient as an adjunctive treatment to fluid diuresis and drug therapy. This was done primarily by examining comprehensive chemistry panels and kidney health profiles taken during treatment of the patients and making statistical inferences from the data set using single factor analysis of variance models. These values were then compared to healthy patient reference intervals as a measure of efficacy

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