JDJCSET | Earth and Environmental Sciences Poster Session
Water Solubility of Chalcones for Safer Aqueous Applications
Academic Level at Time of Presentation
Senior
Major
Chemistry Polymer/Material Science
Minor
Art
List all Project Mentors & Advisor(s)
Dr. Grace Eder, PhD
Presentation Format
Poster Presentation
Abstract/Description
Chalcones are a group of synthetic and naturally occurring small molecules containing two aromatic rings separated by an α,β-unsaturated carbonyl moiety. Chalcones are a versatile motif for organic synthesis, noted for their ability to act as Michael acceptors. They are a starting place for drug development, photodynamic therapy, and for the creation of organic materials. An issue relevant to all these fields is water solubility. Therefore, this study presents a small library of hydroxymethyl chalcones appended with a variety of solubilizing groups, and the effect of those groups on water solubility of the resulting chalcones. This series of novel chalcones represents a set of new building blocks which may be useful on the road to making more specially tailored, aqueous soluble compounds for a variety of less hazardous production applications.
Fall Scholars Week 2022 Event
Earth and Environmental Sciences Poster Session
Water Solubility of Chalcones for Safer Aqueous Applications
Chalcones are a group of synthetic and naturally occurring small molecules containing two aromatic rings separated by an α,β-unsaturated carbonyl moiety. Chalcones are a versatile motif for organic synthesis, noted for their ability to act as Michael acceptors. They are a starting place for drug development, photodynamic therapy, and for the creation of organic materials. An issue relevant to all these fields is water solubility. Therefore, this study presents a small library of hydroxymethyl chalcones appended with a variety of solubilizing groups, and the effect of those groups on water solubility of the resulting chalcones. This series of novel chalcones represents a set of new building blocks which may be useful on the road to making more specially tailored, aqueous soluble compounds for a variety of less hazardous production applications.