JDJCSET | Earth and Environmental Sciences Poster Session

Title

Water Solubility of Chalcones for Safer Aqueous Applications

Presenter Information

Grace YocumFollow

Academic Level at Time of Presentation

Senior

Major

Chemistry Polymer/Material Science

Minor

Art

List all Project Mentors & Advisor(s)

Dr. Grace Eder, PhD

Presentation Format

Poster Presentation

Abstract/Description

Chalcones are a group of synthetic and naturally occurring small molecules containing two aromatic rings separated by an α,β-unsaturated carbonyl moiety. Chalcones are a versatile motif for organic synthesis, noted for their ability to act as Michael acceptors. They are a starting place for drug development, photodynamic therapy, and for the creation of organic materials. An issue relevant to all these fields is water solubility. Therefore, this study presents a small library of hydroxymethyl chalcones appended with a variety of solubilizing groups, and the effect of those groups on water solubility of the resulting chalcones. This series of novel chalcones represents a set of new building blocks which may be useful on the road to making more specially tailored, aqueous soluble compounds for a variety of less hazardous production applications.

Fall Scholars Week 2022 Event

Earth and Environmental Sciences Poster Session

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Water Solubility of Chalcones for Safer Aqueous Applications

Chalcones are a group of synthetic and naturally occurring small molecules containing two aromatic rings separated by an α,β-unsaturated carbonyl moiety. Chalcones are a versatile motif for organic synthesis, noted for their ability to act as Michael acceptors. They are a starting place for drug development, photodynamic therapy, and for the creation of organic materials. An issue relevant to all these fields is water solubility. Therefore, this study presents a small library of hydroxymethyl chalcones appended with a variety of solubilizing groups, and the effect of those groups on water solubility of the resulting chalcones. This series of novel chalcones represents a set of new building blocks which may be useful on the road to making more specially tailored, aqueous soluble compounds for a variety of less hazardous production applications.