Honors College Senior Thesis Presentations
Quantitative and qualitative analysis of mutation in pam-1 of model organism, C. elegans
Academic Level at Time of Presentation
Senior
Major
Biology
Minor
Chemistry
List all Project Mentors & Advisor(s)
Dr. Chris Trzepacz
Presentation Format
Oral Presentation
Abstract/Description
The pam-1 gene in the model roundworm Caenorhabditis elegans governs meiotic exit and establishment of polarity in the single-celled C. elegans embryo. Mutation of the pam-1 gene results in reduced fertility and fecundity in adult C. elegans and disrupts the anatomy of the germinal gonad. The aim of this study is to qualitatively and quantitatively define the changes in the germline cells associated with mutations to the pam-1 gene. Specifically, we will examine the stages of germ cell development within the gonads of adult worms, both wild-type and pam-1 compromised, and identify the changes in the length of the mitotic, transition, and pachytene stages.
Spring Scholars Week 2023 Event
Honors College Senior Thesis Presentations
Quantitative and qualitative analysis of mutation in pam-1 of model organism, C. elegans
The pam-1 gene in the model roundworm Caenorhabditis elegans governs meiotic exit and establishment of polarity in the single-celled C. elegans embryo. Mutation of the pam-1 gene results in reduced fertility and fecundity in adult C. elegans and disrupts the anatomy of the germinal gonad. The aim of this study is to qualitatively and quantitatively define the changes in the germline cells associated with mutations to the pam-1 gene. Specifically, we will examine the stages of germ cell development within the gonads of adult worms, both wild-type and pam-1 compromised, and identify the changes in the length of the mitotic, transition, and pachytene stages.