University of Kentucky
STUDY 1: The Effect of Nutritional Support on Weaning Outcome in Adult Patients Receiving Mechanical Ventilation
Institution
University of Kentucky
Faculty Advisor/ Mentor
Susan Frazier
Abstract
Nutritional support is a major issue for critically ill ventilated patients because as many as 40% of intensive care patients are malnourished. Nutritional support for patients who require mechanical ventilation improves patient outcome by enhancing immune function, respiratory muscle function and ventilatory drive. There are no recent studies that evaluate nutritional support and weaning outcome. Purpose: To describe the nutritional support practices and determine the effect of nutritional support on weaning outcome in patients supported by mechanical ventilation Methods: This is a retrospective medical records review being conducted at an academic medical center. A random sample of 225 patients was chosen from a list of all patients who received mechanical ventilation (n = 613) from January 1 through June 30, 2007. Nutritional support, defined as enteral or parenteral solutions administered, will be evaluated by calories prescribed and administered, route administered, biomarkers of nutritional state and cumulative fluid balance. Nutritional state will be evaluated during the time the patient received ventilation and weaning outcome will be determined. Descriptive statistics will characterize nutritional support practices. T tests and chi square analysis will be used to compare nutritional support between patients who were successfully weaned and those who were not. Results: Data collection is anticipated to be completed by January 1, 2008. Conclusions: These data will provide information about the current practices related to nutritional support for patients who require mechanical ventilation and determine the effect of nutritional support on weaning outcome.
STUDY 1: The Effect of Nutritional Support on Weaning Outcome in Adult Patients Receiving Mechanical Ventilation
Nutritional support is a major issue for critically ill ventilated patients because as many as 40% of intensive care patients are malnourished. Nutritional support for patients who require mechanical ventilation improves patient outcome by enhancing immune function, respiratory muscle function and ventilatory drive. There are no recent studies that evaluate nutritional support and weaning outcome. Purpose: To describe the nutritional support practices and determine the effect of nutritional support on weaning outcome in patients supported by mechanical ventilation Methods: This is a retrospective medical records review being conducted at an academic medical center. A random sample of 225 patients was chosen from a list of all patients who received mechanical ventilation (n = 613) from January 1 through June 30, 2007. Nutritional support, defined as enteral or parenteral solutions administered, will be evaluated by calories prescribed and administered, route administered, biomarkers of nutritional state and cumulative fluid balance. Nutritional state will be evaluated during the time the patient received ventilation and weaning outcome will be determined. Descriptive statistics will characterize nutritional support practices. T tests and chi square analysis will be used to compare nutritional support between patients who were successfully weaned and those who were not. Results: Data collection is anticipated to be completed by January 1, 2008. Conclusions: These data will provide information about the current practices related to nutritional support for patients who require mechanical ventilation and determine the effect of nutritional support on weaning outcome.